SWEDISH DIABETES RESEARCH

Publikationlista Henrik Ortsäter

Originalarbeten

Ortsäter H, Liss P, Lund P-E, Åkerman K.E.O. and Bergsten P. Dynamic measurements of oxygen tension in islets of Langerhans. Adv. Exp. Med Biol. (1999) 471:367-372

Ortsäter H, Liss P, Lund P-E, Åkerman K.E.O. and Bergsten P. Oscillations in oxygen tension and insulin release of individual ob/ob mouse islets. Diabetologia (2000) 43:1313-1318

Westerlund J, Ortsäter H, Palm F, Sundsten T, and Bergsten P. Glucose-regulated pulsatile insulin release from mouse islets via the KATP channel- independent pathway. European journal of endocrinology (2001) 144:667-675

Lin J-M, Ortsäter H, Galli J, Luthman H and Bergsten P. Phenotyping of individual pancreatic islets locates genetic defects in stimulus secretion coupling to Niddm1i within the major diabetes locus in GK rats. Diabetes (2001) 50:2737-2743

Ortsäter H, Liss P, Åkerman K.E.O. and Bergsten P. Contribution of glycolytic and mitochondrial pathways in glucose-induced changes in islet respiration and insulin secretion. Pflügers Archiv European Journal of Physiology (2002) 444:506-512

Palm F, Ortsäter H, Hansell P, Liss P and Carlsson PO. Differentiating between effects of streptozotocin per se and subsequent hyperglycaemia on renal function and metabolism in the streptozotocin-diabetic rat model. Diabetes/Metabolism Research and Reviews (2004) 20:452-459.

Ortsäter H, Alberts P, Warpman U, Engblom L OM, Abrahmsén L and Bergsten P. Regulation of 11β-hydroxysteroid dehydrogenase type 1 and glucose-stimulated insulin secretion in pancreatic islets of Langerhans. Diabetes/Metabolism Research and Reviews (2005) 21:359-366.

Hernández-Fisac I, Fernández-Pascual S, Ortsäter H, Pizarro-Delgado J, Martín del Río R, Bergsten P, Tamarit-Rodriguez J. Oxo-4-methylpentanoic acid directs the metabolism of GABA into the citric acid cycle in rat pancreatic islets. Biochemical Journal (2006) 400:81-89.

Ortsäter H, Sundsten T, Lin J-M, and Bergsten P. Evaluation of the SELDI-TOF MS technique for protein profiling of pancreatic islets exposed to glucose and oleate. Proteomics (2007) 7:3105-3115.

REVIEWS:

Ortsäter H and Bergsten P. Protein profiling of pancreatic islets. Expert Reviews of Proteomics (2006) Dec 3(6):665-675.

Ortsäter H and Sjöholm Å. A busy cell - Endoplasmic reticulum stress in the pancreatic -cell. Mol Cell Endocrinol. (2007) 277(1-2):1-5.

ABSTRACTS:

Westerlund J, Ortsäter H, Palm F, Sundsten T and Bergsten P. Glucose-induced pulsatile release of insulin independent of ATP-sensitive K+ channels. Diabetologia 40: 100A, 1997

Ortsäter H, Liss P, Lund PE, Åkerman K, Bergsten P. Synchronous oscillations in oxygen tension and insulin release of individual mouse islets. Diabetologia 41: (Suppl 1) 23A, 1998.

Sundsten T, Ortsäter H and Bergsten P. Inhibition if intrapancreatic ganglia causes sustained and non-oscillatory insulin release from the perfused pancreas. Diabetologia 41: (Suppl 1) 76A, 1998.

Ortsäter H, Liss P, Åkerman K, Bergsten P. Potentiation of glucose-induced insulin release without corresponding changes in oxygen consumption. Diabetologia (Suppl) 42:126A, 1999.

Lin JM, Ortsäter H, Galli J, Fakhrai-Rad H, Luthman H and Bergsten P. Islets from congenic strain for major GK diabetes locus lack secretory response to glucose. Diabetologia (Suppl 1) 43: 131A, 2000.

Ortsäter H, Abrahmsen L, Björkstrand E, Warpman U and Bergsten P. 11β-Hydroxysteriod Dehydrogenase Type 1 protein is important for glucose-induced insulin release. Diabetes (Suppl 2) 51 A390, 2002

Sundsten T, Ortsäter H and Bergsten P. Prolonged culturing increases early and late insulin release in KKAy-mouse islets which correlates with changes in islet protein profiles. Diabetologia 46: (Suppl 6) A446, 2003.

Ortsäter H, Sundsten T, Lin J-M, and Bergsten P. Islet proteins implicated in glucose- and lipid-induced metabolic and secretory alterations identified by correlating islet phenotype with islet global protein patterns. Diabetologia 46: (Suppl 6) A509, 2003.

Ortsäter H, Sundsten T and Bergsten P. Protein expression in pancreatic islets exposed to fatty acids with different chain length and degree of saturation. Diabetologia 47: (Suppl 1) A483, 2004.

Ortsäter H, Thörn K, Sargsyan E and Bergsten P. Unfolded protein response in fatty acid treated pancreatic β-cells. Diabetologia 49: (Suppl 1) 0100, 2006.

Gillberg P, Ortsäter H and Bergsten P. Changes in jejunal enterocyte protein patterns involving endoplasmic reticulum (ER)-stress in mice fed a high fat diet. Gastroenterology 132:4 (Suppl 2) T1929, 2007.

Grankvist N, Ortsäter H, Zhang Q, Honkanen R and Sjöholm Å. Glucose and dexamethasone regulation of serine/threonine protein phosphatase 5 in normoglycaemic and hyperglycaemic human and rat islets. Diabetologia 50: (Suppl 1) 0512, 2007.